Rare Cause of Cardiotoxicity

Dalvir Gill; Kamalpreet Mann; Sharanpreet Kaur; Vanessa Goyes Ruiz; Ryan Dean; Samana Zaidi

doi:10.21767/1989-5216.1000201

Abstract

Rare Cause of Cardiotoxicity

Etoposide based combination chemotherapy is used with curative intent in patients with advanced testicular germ cell tumors. Common side effects involve nausea and vomiting (up to 43%), alopecia (up to 66%), leukopenia (up to 91%). Cardiovascular side effects are rare, and hypotension only occurs in 1%-2% of patients. Etoposide is not known to cause thyroid dysfunction. We observed a case of bradycardia and QTc interval shortening after introduction of etoposide based chemotherapy.

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