Reach Us +44-1235-425476

Abstract

Developments on the physiopathology of rheumatoid arthritis, Time for a new theory?

Rheumatoid Arthritis (RA) is one of the three diseases most commonly seen in rheumatology consultation being cause of a great demand in health care services globally. Its etiology remains unknown, and although attempts have been made to recognize the target auto-antigens, it is still unknown. The immune response of these patients is characterized by the involvement of multiple cells and effectors molecular inflammatory mechanisms. However, from this complex view emer- ges a common point, it is, the escape of the mechanisms of immune control. Understanding of reason and sense of loss of tolerance, the activation of auto-reactive T cells and the generation of auto antibodies is fundamental to understand the physiopathology of rheumatoid arthritis and develop specific immune-therapeutic strategies.


Author(s): Arnulfo Nava

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
Flyer image

Abstracted/Indexed in

  • Index Copernicus
  • Google Scholar
  • Genamics JournalSeek
  • Directory of Research Journal Indexing (DRJI)
  • WorldCat
  • Proquest Summons
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Secret Search Engine Labs