Title: Acid uric and other cardiovascular risk factors control in the primary care settings in the community.
Background: Hyperuricaemia represents nowaday the newer risk factor for cardiovascular di-seases. Epidemiologic data shows, that its prevalence differs in various populations signifi-cantly from 4% up to 40% with race and geographical variables. Prevalence data and its con-trol in our patient´s population are missing yet. From The Framingham data relative risk was estimated of 25% for cardiovascular diseases, coronary heart disease and all-course mortality. The purpose of the survey was to bring the registry data as the source for the further evalua-tion and secondary prevention measures.
Methods: 330 primary care physicians in the country were asked to participate for the survey Mirror Slovakia. Hyperuricaemia and other main cardiovascular risk factors were evaluated from the sample of 20 000 patients from the primary care physician´s registries. Final data were obtained from 19,644 patients having all three controls: baseline, at 6th and 12th months. Risk factor control and medical therapy was evaluated from the medical records and pa-tient´s diaries in order to see the primary care in the community settings.
Findings: High prevalence of the main risk factors was seen to contributing to very high glo-bal cardiovascular risk of our patients in the community. This corresponds with the current one of the highest cardiovascular mortality in Europe. Significant higher acid uric concentra-tions among treated patients was seen in men, but not in women. The most often used diure-tic hydrochlorothiazide was in clinical practice of hypertension. Hyperuricemia was more prevalent among patients treated with hydrochlorothiazide both in men and in women. Selec-tion of types of antihypertensives with uricosuric effects may contribute to the improvement of the metabolic changes among treated high risk patients.
Conclusions: Obtained data for the national registry are the source for the improvement in risk factor control and secondary prevention in daily clinical practice in the country.