Figure 1: Components of the Mammalian Target of Rapamycin (mTOR) complexes. The mTOR serine/threonine protein kinase catalytic subunit enucleates the center of both mTOR complexes. mTOR complexes have some unique partners and some shared partners between the two complexes. mTORC1 consists of mTOR catalytic subunit exclusively contains Raptor (regulatory associated protein of mTOR) and ); PRAS 40 (AKT/PKA substrate 40 kDa protein; and shares mLST/GβL (mammalian lethal with sec13 protein 8/G-protein β-protein subunit likeDeptor (DEP-domain-containing mTORinteracting protein.